The simple answer is yes, the RevealPrint solution works with every direct thermal label printer on the market. We suggest you test before placing an order. What we have found that with older model direct thermal printers or a label printer with high use, the printhead gets worn down and needs to be replaced. We have a complete line of bar code printheads available as well to keep your labels looking perfect. For samples of this exciting new color labeling product, please Email or call 888.972.5234.